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Step off the brake

Author: admin

Forgetfulness need not be synonymous with ageing. Researchers at the University of California-Irvine have identified that a molecular brake pad, called HDAC3, is a major culprit in the ageing brain’s lack of flexibility to house and encode information. As Dr Marcelo Wood, senior author of the study, tells website, the brake pad attempts to compact DNA, resulting in the obstruction of a gene located in the hippocampus that plays a role in programming biological processes in cells. Lifting the brake pad could allow the ageing brain access to the gene, facilitating the formation of memories once again. The study, presented at the American Association for Advancement Science in Texas, holds promise for drug development and treatment to improve memory formation in ageing brains.

Photo: iStock
Featured in Harmony — Celebrate Age Magazine
April 2018